NLRP6 Negatively Regulates Innate Immunity and Host Defense Against Bacterial Pathogens
Members of the intracellular nucleotide-binding and oligomerization domain (NOD)-like receptor (NLR) family contribute to immune responses through activation of NF-κB, type I interferon and inflammasome signaling1. Mice lacking the NLR family member NLRP6 were recently shown to be susceptible to col...
Main Authors: | Anand, Paras K., Malireddi, R. K. Subbarao, Lukens, John R., Vogel, Peter, Bertin, John, Lamkanfi, Mohamed, Kanneganti, Thirumala-Devi |
---|---|
Format: | Online |
Language: | English |
Published: |
2012
|
Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3422416/ |
Similar Items
-
Role of the Nlrp3 Inflammasome in Microbial Infection
by: Anand, Paras K., et al.
Published: (2011) -
Innate Immune Pathways in Host Defense
by: Kanneganti, Thirumala-Devi, et al.
Published: (2012) -
Chronic TLR Stimulation Controls NLRP3 Inflammasome Activation through IL-10 Mediated Regulation of NLRP3 Expression and Caspase-8 Activation
by: Gurung, Prajwal, et al.
Published: (2015) -
Role of type I interferons in inflammasome activation, cell death, and disease during microbial infection
by: Malireddi, R. K. Subbarao, et al.
Published: (2013) -
Reactive Oxygen Species Regulate Caspase-11 Expression and Activation of the Non-canonical NLRP3 Inflammasome during Enteric Pathogen Infection
by: Lupfer, Christopher R., et al.
Published: (2014)