Role of the Nlrp3 Inflammasome in Microbial Infection

The intracellular Nod-like receptor Nlrp3 has emerged as the most versatile innate immune receptor because of its broad specificity in mediating immune response to a wide range of microbial or danger signals. Nlrp3 mediates assembly of the inflammasome complex in the presence of microbial components...

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Bibliographic Details
Main Authors: Anand, Paras K., Malireddi, R. K. Subbarao, Kanneganti, Thirumala-Devi
Format: Online
Language:English
Published: Frontiers Research Foundation 2011
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3109351/