The cell biology of inflammasomes: Mechanisms of inflammasome activation and regulation

Over the past decade, numerous advances have been made in the role and regulation of inflammasomes during pathogenic and sterile insults. An inflammasome complex comprises a sensor, an adaptor, and a zymogen procaspase-1. The functional output of inflammasome activation includes secretion of cytokin...

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Bibliographic Details
Main Authors: Sharma, Deepika, Kanneganti, Thirumala-Devi
Format: Online
Language:English
Published: The Rockefeller University Press 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4915194/