Inflammasomes: Caspase-1-Activating Platforms with Critical Roles in Host Defense
Activation of the inflammatory cysteine protease caspase-1 in inflammasome complexes plays a critical role in the host response to microbial infections. Inflammasome activation induces inflammation through secretion of the pro-inflammatory cytokines interleukin (IL)-1β and IL-18 and through extracel...
| Main Authors: | , |
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| Format: | Online |
| Language: | English |
| Published: |
Frontiers Research Foundation
2011
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3109324/ |