Role of type I interferons in inflammasome activation, cell death, and disease during microbial infection
Interferons (IFNs) were discovered over a half-century ago as antiviral factors. The role of type I IFNs has been studied in the pathogenesis of both acute and chronic microbial infections. Deregulated type I IFN production results in a damaging cascade of cell death, inflammation, and immunological...
| Main Authors: | , |
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| Format: | Online |
| Language: | English |
| Published: |
Frontiers Media S.A.
2013
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3824101/ |