Neoplastic cells are a rare component in human glioblastoma microvasculature

by Rodriguez, Fausto J., Orr, Brent A., Ligon, Keith L., Eberhart, Charles G.
Published 2012

Brain and Testicular Tumors in Mice with Progenitor Cells Lacking BAX and BAK

by Katz, Samuel G., Fisher, Jill K., Correll, Mick, Bronson, Roderick T., Ligon, Keith L., Walensky, Loren D.
Published 2012

Delivery of Functional Anti-miR-9 by Mesenchymal Stem Cell–derived Exosomes to Glioblastoma Multiforme Cells Conferred Chemosensitivity

by Munoz, Jessian L, Bliss, Sarah A, Greco, Steven J, Ramkissoon, Shakti H, Ligon, Keith L, Rameshwar, Pranela
Published 2013

Temozolomide resistance in glioblastoma occurs by miRNA-9-targeted PTCH1, independent of sonic hedgehog level

by Munoz, Jessian L., Rodriguez-Cruz, Vivian, Ramkissoon, Shakti H., Ligon, Keith L., Greco, Steven J., Rameshwar, Pranela
Published 2015

Prominin-1 (CD133) Defines Both Stem and Non-Stem Cell Populations in CNS Development and Gliomas

by Holmberg Olausson, Karl, Maire, Cecile L., Haidar, Sam, Ling, Jason, Learner, Emily, Nistér, Monica, Ligon, Keith L.
Published 2014

Somatic mutations associated with MRI-derived volumetric features in glioblastoma

by Gutman, David A., Dunn, William D., Grossmann, Patrick, Cooper, Lee A. D., Holder, Chad A., Ligon, Keith L., Alexander, Brian M., Aerts, Hugo J. W. L.
Published 2015

Case Report: Next generation sequencing identifies a NAB2-STAT6 fusion in Glioblastoma

by Diamandis, Phedias, Ferrer-Luna, Ruben, Huang, Raymond Y., Folkerth, Rebecca D., Ligon, Azra H., Wen, Patrick Y., Beroukhim, Rameen, Ligon, Keith L., Ramkissoon, Shakti H.
Published 2016

BRAF V600E Mutations Are Common in Pleomorphic Xanthoastrocytoma: Diagnostic and Therapeutic Implications

by Dias-Santagata, Dora, Lam, Quynh, Vernovsky, Kathy, Vena, Natalie, Lennerz, Jochen K., Borger, Darrell R., Batchelor, Tracy T., Ligon, Keith L., Iafrate, A. John, Ligon, Azra H., Louis, David N., Santagata, Sandro
Published 2011

Somatic Mutations of PIK3R1 Promote Gliomagenesis

by Quayle, Steven N., Lee, Jennifer Y., Cheung, Lydia W T., Ding, Li, Wiedemeyer, Ruprecht, Dewan, Robert W., Huang-Hobbs, Emmet, Zhuang, Li, Wilson, Richard K., Ligon, Keith L., Mills, Gordon B., Cantley, Lewis C., Chin, Lynda
Published 2012

Transformation by the R Enantiomer of 2-Hydroxyglutarate Linked to EglN Activation

by Koivunen, Peppi, Lee, Sungwoo, Duncan, Christopher G., Lopez, Giselle, Lu, Gang, Ramkissoon, Shakti, Losman, Julie A., Joensuu, Päivi, Bergmann, Ulrich, Gross, Stefan, Travins, Jeremy, Weiss, Samuel, Looper, Ryan, Ligon, Keith L., Verhaak, Roel G.W., Yan, Hai, Kaelin, William G.
Published 2012

Integrative functional genomics identifies RINT1 as a novel GBM oncogene

by Quayle, Steven N., Chheda, Milan G., Shukla, Sachet A., Wiedemeyer, Ruprecht, Tamayo, Pablo, Dewan, Robert W., Zhuang, Li, Huang-Hobbs, Emmet, Haidar, Sam, Xiao, Yonghong, Ligon, Keith L., Hahn, William C., Chin, Lynda
Published 2012

DNA Fragmentation Simulation Method (FSM) and Fragment Size Matching Improve aCGH Performance of FFPE Tissues

by Craig, Justin M., Vena, Natalie, Ramkissoon, Shakti, Idbaih, Ahmed, Fouse, Shaun D., Ozek, Memet, Sav, Aydin, Hill, D. Ashley, Margraf, Linda R., Eberhart, Charles G., Kieran, Mark W., Norden, Andrew D., Wen, Patrick Y., Loda, Massimo, Santagata, Sandro, Ligon, Keith L., Ligon, Azra H.
Published 2012

Genomic sequencing of meningiomas identifies oncogenic SMO and AKT1 mutations

by Brastianos, Priscilla K., Horowitz, Peleg M., Santagata, Sandro, Jones, Robert T., McKenna, Aaron, Getz, Gad, Ligon, Keith L., Palescandolo, Emanuele, Van Hummelen, Paul, Ducar, Matthew D., Raza, Alina, Sunkavalli, Ashwini, MacConaill, Laura E., Stemmer-Rachamimov, Anat O., Louis, David N., Hahn, William C., Dunn, Ian F., Beroukhim, Rameen
Published 2013

Zebrafish neurofibromatosis type 1 genes have redundant functions in tumorigenesis and embryonic development

by Shin, Jimann, Padmanabhan, Arun, de Groh, Eric D., Lee, Jeong-Soo, Haidar, Sam, Dahlberg, Suzanne, Guo, Feng, He, Shuning, Wolman, Marc A., Granato, Michael, Lawson, Nathan D., Wolfe, Scot A., Kim, Seok-Hyung, Solnica-Krezel, Lilianna, Kanki, John P., Ligon, Keith L., Epstein, Jonathan A., Look, A. Thomas
Published 2012

P53 and Pten control neural and glioma stem/progenitor cell renewal and differentiation

by Zheng, Hongwu, Ying, Haoqiang, Yan, Haiyan, Kimmelman, Alec C., Hiller, David J., Chen, An-Jou, Perry, Samuel R., Tonon, Giovanni, Chu, Gerald C., Ding, Zhihu, Stommel, Jayne M., Dunn, Katherine L., Wiedemeyer, Ruprecht, You, Mingjian J., Brennan, Cameron, Wang, Y. Alan, Ligon, Keith L., Wong, Wing H., Chin, Lynda, DePinho, Ronald A.
Published 2008

Increased expression of the immune modulatory molecule PD-L1 (CD274) in anaplastic meningioma

by Du, Ziming, Abedalthagafi, Malak, Aizer, Ayal A., McHenry, Allison R., Sun, Heather H., Bray, Mark-Anthony, Viramontes, Omar, Machaidze, Revaz, Brastianos, Priscilla K., Reardon, David A., Dunn, Ian F., Freeman, Gordon J., Ligon, Keith L., Carpenter, Anne E., Alexander, Brian M., Agar, Nathalie Y., Rodig, Scott J., Bradshaw, Elizabeth M., Santagata, Sandro
Published 2014

SHMT2 drives glioma cell survival in the tumor microenvironment but imposes a dependence on glycine clearance

by Kim, Dohoon, Fiske, Brian P., Birsoy, Kivanc, Freinkman, Elizaveta, Kami, Kenjiro, Possemato, Richard, Chudnovsky, Yakov, Pacold, Michael E., Chen, Walter W., Cantor, Jason R., Shelton, Laura M., Gui, Dan Y., Kwon, Manjae, Ramkissoon, Shakti H., Ligon, Keith L., Kang, Seong Woo, Snuderl, Matija, Heiden, Matthew G. Vander, Sabatini, David M.
Published 2015

MAPK activation and HRAS mutation identified in pituitary spindle cell oncocytoma

by Miller, Michael B., Bi, Wenya Linda, Ramkissoon, Lori A., Kang, Yun Jee, Abedalthagafi, Malak, Knoff, David S., Agarwalla, Pankaj K., Wen, Patrick Y., Reardon, David A., Alexander, Brian M., Laws, Edward R., Dunn, Ian F., Beroukhim, Rameen, Ligon, Keith L., Ramkissoon, Shakti H.
Published 2016

Spatial and temporal homogeneity of driver mutations in diffuse intrinsic pontine glioma

by Nikbakht, Hamid, Panditharatna, Eshini, Mikael, Leonie G., Li, Rui, Gayden, Tenzin, Osmond, Matthew, Ho, Cheng-Ying, Kambhampati, Madhuri, Hwang, Eugene I., Faury, Damien, Siu, Alan, Papillon-Cavanagh, Simon, Bechet, Denise, Ligon, Keith L., Ellezam, Benjamin, Ingram, Wendy J., Stinson, Caedyn, Moore, Andrew S., Warren, Katherine E., Karamchandani, Jason, Packer, Roger J., Jabado, Nada, Majewski, Jacek, Nazarian, Javad
Published 2016

Specific detection of methionine 27 mutation in histone 3 variants (H3K27M) in fixed tissue from high-grade astrocytomas

by Bechet, Denise, Gielen, Gerrit G. H., Korshunov, Andrey, Pfister, Stefan M., Rousso, Caterina, Faury, Damien, Fiset, Pierre-Olivier, Benlimane, Naciba, Lewis, Peter W., Lu, Chao, David Allis, C., Kieran, Mark W., Ligon, Keith L., Pietsch, Torsten, Ellezam, Benjamin, Albrecht, Steffen, Jabado, Nada
Published 2014