Chaperones as thermodynamic sensors of drug–target interactions reveal kinase inhibitor specificities in living cells

by Taipale, Mikko, Krykbaeva, Irina, Whitesell, Luke, Santagata, Sandro, Zhang, Jianming, Liu, Qingsong, Gray, Nathanael S., Lindquist, Susan
Published 2013

Rapid Selection of Cyclic Peptides that Reduce α-Synuclein Toxicity in Yeast and Animal Models

by Kritzer, Joshua A., Hamamichi, Shusei, McCaffery, J. Michael, Santagata, Sandro, Naumann, Todd A., Caldwell, Kim A., Caldwell, Guy A., Lindquist, Susan
Published 2009

Eastern Equine Encephalitis in Children, Massachusetts and New Hampshire,USA, 1970–2010

by Silverman, Michael A., Misasi, John, Smole, Sandra, Feldman, Henry A., Cohen, Adam B., Santagata, Sandro, McManus, Michael, Ahmed, Asim A.
Published 2013

Atypical presentation of cerebral schistosomiasis four years after exposure to Schistosoma mansoni☆

by Rose, Matthew F., Zimmerman, Eli E., Hsu, Liangge, Golby, Alexandra J., Saleh, Emam, Folkerth, Rebecca D., Santagata, Sandro S., Milner, Danny A., Ramkissoon, Shakti H.
Published 2014

BRAF V600E Mutations Are Common in Pleomorphic Xanthoastrocytoma: Diagnostic and Therapeutic Implications

by Dias-Santagata, Dora, Lam, Quynh, Vernovsky, Kathy, Vena, Natalie, Lennerz, Jochen K., Borger, Darrell R., Batchelor, Tracy T., Ligon, Keith L., Iafrate, A. John, Ligon, Azra H., Louis, David N., Santagata, Sandro
Published 2011

The Master Regulator of the Cellular Stress Response (HSF1) Is Critical for Orthopoxvirus Infection

by Filone, Claire Marie, Caballero, Ignacio S., Dower, Ken, Mendillo, Marc L., Cowley, Glenn S., Santagata, Sandro, Rozelle, Daniel K., Yen, Judy, Rubins, Kathleen H., Hacohen, Nir, Root, David E., Hensley, Lisa E., Connor, John
Published 2014

Compromising the 19S proteasome complex protects cells from reduced flux through the proteasome

by Tsvetkov, Peter, Mendillo, Marc L, Zhao, Jinghui, Carette, Jan E, Merrill, Parker H, Cikes, Domagoj, Varadarajan, Malini, van Diemen, Ferdy R, Penninger, Josef M, Goldberg, Alfred L, Brummelkamp, Thijn R, Santagata, Sandro, Lindquist, Susan
Published 2015

DNA Fragmentation Simulation Method (FSM) and Fragment Size Matching Improve aCGH Performance of FFPE Tissues

by Craig, Justin M., Vena, Natalie, Ramkissoon, Shakti, Idbaih, Ahmed, Fouse, Shaun D., Ozek, Memet, Sav, Aydin, Hill, D. Ashley, Margraf, Linda R., Eberhart, Charles G., Kieran, Mark W., Norden, Andrew D., Wen, Patrick Y., Loda, Massimo, Santagata, Sandro, Ligon, Keith L., Ligon, Azra H.
Published 2012

Genomic sequencing of meningiomas identifies oncogenic SMO and AKT1 mutations

by Brastianos, Priscilla K., Horowitz, Peleg M., Santagata, Sandro, Jones, Robert T., McKenna, Aaron, Getz, Gad, Ligon, Keith L., Palescandolo, Emanuele, Van Hummelen, Paul, Ducar, Matthew D., Raza, Alina, Sunkavalli, Ashwini, MacConaill, Laura E., Stemmer-Rachamimov, Anat O., Louis, David N., Hahn, William C., Dunn, Ian F., Beroukhim, Rameen
Published 2013

Molecular imaging of drug transit through the blood-brain barrier with MALDI mass spectrometry imaging

by Liu, Xiaohui, Ide, Jennifer L., Norton, Isaiah, Marchionni, Mark A., Ebling, Maritza C., Wang, Lan Y., Davis, Erin, Sauvageot, Claire M., Kesari, Santosh, Kellersberger, Katherine A., Easterling, Michael L., Santagata, Sandro, Stuart, Darrin D., Alberta, John, Agar, Jeffrey N., Stiles, Charles D., Agar, Nathalie Y. R.
Published 2013

Increased expression of the immune modulatory molecule PD-L1 (CD274) in anaplastic meningioma

by Du, Ziming, Abedalthagafi, Malak, Aizer, Ayal A., McHenry, Allison R., Sun, Heather H., Bray, Mark-Anthony, Viramontes, Omar, Machaidze, Revaz, Brastianos, Priscilla K., Reardon, David A., Dunn, Ian F., Freeman, Gordon J., Ligon, Keith L., Carpenter, Anne E., Alexander, Brian M., Agar, Nathalie Y., Rodig, Scott J., Bradshaw, Elizabeth M., Santagata, Sandro
Published 2014

Clinical multiplexed exome sequencing distinguishes adult oligodendroglial neoplasms from astrocytic and mixed lineage gliomas

by Cryan, Jane B., Haidar, Sam, Ramkissoon, Lori A., Bi, Wenya Linda, Knoff, David S., Schultz, Nikolaus, Abedalthagafi, Malak, Brown, Loreal, Wen, Patrick Y., Reardon, David A., Dunn, Ian F., Folkerth, Rebecca D., Santagata, Sandro, Lindeman, Neal I., Ligon, Azra H., Beroukhim, Rameen, Hornick, Jason L., Alexander, Brian M., Ligon, Keith L., Ramkissoon, Shakti H.
Published 2014

Angiomatous meningiomas have a distinct genetic profile with multiple chromosomal polysomies including polysomy of chromosome 5

by Abedalthagafi, Malak S., Merrill, Parker H., Bi, Wenya Linda, Jones, Robert T., Listewnik, Marc L., Ramkissoon, Shakti H., Thorner, Aaron R., Dunn, Ian F., Beroukhim, Rameen, Alexander, Brian M., Brastianos, Priscilla K., Francis, Joshua M., Folkerth, Rebecca D., Ligon, Keith L., Hummelen, Paul Van, Ligon, Azra H., Santagata, Sandro
Published 2014

A HIF1α Regulatory Loop Links Hypoxia and Mitochondrial Signals in Pheochromocytomas

by Dahia, Patricia L. M, Ross, Ken N, Wright, Matthew E, Hayashida, César Y, Santagata, Sandro, Barontini, Marta, Kung, Andrew L, Sanso, Gabriela, Powers, James F, Tischler, Arthur S, Hodin, Richard, Heitritter, Shannon, Moore, Francis, Dluhy, Robert, Sosa, Julie Ann, Ocal, I. Tolgay, Benn, Diana E, Marsh, Deborah J, Robinson, Bruce G, Schneider, Katherine, Garber, Judy, Arum, Seth M, Korbonits, Márta, Grossman, Ashley, Pigny, Pascal, Toledo, Sérgio P. A, Nosé, Vania, Li, Cheng, Stiles, Charles D
Published 2005

Sporadic hemangioblastomas are characterized by cryptic VHL inactivation

by Shankar, Ganesh M, Taylor-Weiner, Amaro, Lelic, Nina, Jones, Robert T, Kim, James C, Francis, Joshua M, Abedalthagafi, Malak, Borges, Lawrence F, Coumans, Jean-Valery, Curry, William T, Nahed, Brian V, Shin, John H, Paek, Sun Ha, Park, Sung-Hye, Stewart, Chip, Lawrence, Michael S, Cibulskis, Kristian, Thorner, Aaron R, Van Hummelen, Paul, Stemmer-Rachamimov, Anat O, Batchelor, Tracy T, Carter, Scott L, Hoang, Mai P, Santagata, Sandro, Louis, David N, Barker, Fred G, Meyerson, Matthew, Getz, Gad, Brastianos, Priscilla K, Cahill, Daniel P
Published 2014

Exome sequencing identifies BRAF mutations in papillary craniopharyngiomas

by Brastianos, Priscilla K., Taylor-Weiner, Amaro, Manley, Peter E., Jones, Robert T., Dias-Santagata, Dora, Thorner, Aaron R., Rodriguez, Fausto J., Bernardo, Lindsay A., Schubert, Laura, Sunkavalli, Ashwini, Shillingford, Nick, Calicchio, Monica L., Lidov, Hart G.W., Taha, Hala, Martinez-Lage, Maria, Santi, Mariarita, Storm, Phillip B., Lee, John Y. K., Palmer, James N., Adappa, Nithin D., Scott, R. Michael, Dunn, Ian F., Laws, Edward R., Stewart, Chip, Ligon, Keith L., Hoang, Mai P., Van Hummelen, Paul, Hahn, William C., Louis, David N., Resnick, Adam C., Kieran, Mark W., Getz, Gad, Santagata, Sandro
Published 2014

MYB-QKI rearrangements in Angiocentric Glioma drive tumorigenicity through a tripartite mechanism

by Bandopadhayay, Pratiti, Ramkissoon, Lori A., Jain, Payal, Bergthold, Guillaume, Wala, Jeremiah, Zeid, Rhamy, Schumacher, Steven E., Urbanski, Laura, O’Rourke, Ryan, Gibson, William J., Pelton, Kristine, Ramkissoon, Shakti H., Han, Harry J., Zhu, Yuankun, Choudhari, Namrata, Silva, Amanda, Boucher, Katie, Henn, Rosemary E., Kang, Yun Jee, Knoff, David, Paolella, Brenton R., Gladden-Young, Adrianne, Varlet, Pascale, Pages, Melanie, Horowitz, Peleg M., Federation, Alexander, Malkin, Hayley, Tracy, Adam, Seepo, Sara, Ducar, Matthew, Hummelen, Paul Van, Santi, Mariarita, Buccoliero, Anna Maria, Scagnet, Mirko, Bowers, Daniel C., Giannini, Caterina, Puget, Stephanie, Hawkins, Cynthia, Tabori, Uri, Klekner, Almos, Bognar, Laszlo, Burger, Peter C., Eberhart, Charles, Rodriguez, Fausto J., Hill, D. Ashley, Mueller, Sabine, Haas-Kogan, Daphne A., Phillips, Joanna J., Santagata, Sandro, Stiles, Charles D., Bradner, James E., Jabado, Nada, Goren, Alon, Grill, Jacques, Ligon, Azra H., Goumnerova, Liliana, Waanders, Angela J., Storm, Phillip B., Kieran, Mark W., Ligon, Keith L., Beroukhim, Rameen, Resnick, Adam C.
Published 2016