MAPK activation and HRAS mutation identified in pituitary spindle cell oncocytoma

MAPK activation and HRAS mutation identified in pituitary spindle cell oncocytoma

Pituitary spindle cell oncocytoma (SCO) is an uncommon primary pituitary neoplasm that presents with mass effect on adjacent neurovascular structures, similar to non-hormone-producing pituitary adenomas. To determine the molecular etiology of SCO, we performed exome sequencing on four SCO cases, wit...

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Bibliographic Details
Main Authors: Miller, Michael B., Bi, Wenya Linda, Ramkissoon, Lori A., Kang, Yun Jee, Abedalthagafi, Malak, Knoff, David S., Agarwalla, Pankaj K., Wen, Patrick Y., Reardon, David A., Alexander, Brian M., Laws, Edward R., Dunn, Ian F., Beroukhim, Rameen, Ligon, Keith L., Ramkissoon, Shakti H.
Format: Online
Language:English
Published: Impact Journals LLC 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5095058/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5095058/

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