Rrp5 Binding at Multiple Sites Coordinates Pre-rRNA Processing and Assembly

Rrp5 Binding at Multiple Sites Coordinates Pre-rRNA Processing and Assembly

In vivo UV crosslinking identified numerous preribosomal RNA (pre-rRNA) binding sites for the large, highly conserved ribosome synthesis factor Rrp5. Intramolecular complementation has shown that the C-terminal domain (CTD) of Rrp5 is required for pre-rRNA cleavage at sites A0–A2 on the pathway of 1...

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Main Authors: Lebaron, Simon, Segerstolpe, Åsa, French, Sarah L., Dudnakova, Tatiana, de lima Alves, Flavia, Granneman, Sander, Rappsilber, Juri, Beyer, Ann L., Wieslander, Lars, Tollervey, David
Format: Online
Language:English
Published: Cell Press 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3991325/

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