Identification of Bacteriophage-Encoded Anti-sRNAs in Pathogenic Escherichia coli

In bacteria, Hfq is a core RNA chaperone that catalyzes the interaction of mRNAs with regulatory small RNAs (sRNAs). To determine in vivo RNA sequence requirements for Hfq interactions, and to study riboregulation in a bacterial pathogen, Hfq was UV crosslinked to RNAs in enterohemorrhagic Escherich...

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Bibliographic Details
Main Authors: Tree, Jai J., Granneman, Sander, McAteer, Sean P., Tollervey, David, Gally, David L.
Format: Online
Language:English
Published: Cell Press 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4104026/