Proof reading of pre-40S ribosome maturation by a translation initiation factor and 60S subunits

In the final steps of yeast ribosome synthesis, immature translation-incompetent pre-40S particles that contain 20S pre-rRNA are converted to the mature translation-competent subunits containing the 18S rRNA. An assay for 20S pre-rRNA cleavage in purified pre-40S particles showed that cleavage by th...

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Bibliographic Details
Main Authors: Lebaron, Simon, Schneider, Claudia, van Nues, Robert W., Swiatkowska, Agata, Walsh, Dietrich, Böttcher, Bettina, Granneman, Sander, Watkins, Nicholas J., Tollervey, David
Format: Online
Language:English
Published: 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3654374/