The nuclear RNA polymerase II surveillance system targets polymerase III transcripts

The exosome and Trf4/5–Air1/2–Mtr4 polyadenylation (TRAMP) complexes together with the Nrd1–Nab3 RNA-binding heterodimer have an important role in RNA surveillance. Here, the global analysis of Nrd1, Nab3 and Trf4 binding sites identifies targets for the nuclear surveillance system, including mRNAs,...

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Bibliographic Details
Main Authors: Wlotzka, Wiebke, Kudla, Grzegorz, Granneman, Sander, Tollervey, David
Format: Online
Language:English
Published: Nature Publishing Group 2011
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3102002/