Box C/D snoRNP catalysed methylation is aided by additional pre-rRNA base-pairing
Box C/D small nucleolar RNPs catalyse 2′-O-methylation of eukaryotic ribosomal RNA. A large-scale analysis of yeast box C/D snoRNAs reveals conserved ‘extra base-pairing' between snoRNAs and regions adjacent to their rRNA methylation site and points to a role for the non-catalytic protein subun...
Main Authors: | , , , , , , |
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Format: | Online |
Language: | English |
Published: |
Nature Publishing Group
2011
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3116282/ |