The DEAH-box Helicase Dhr1 Dissociates U3 from the Pre-rRNA to Promote Formation of the Central Pseudoknot

The DEAH-box Helicase Dhr1 Dissociates U3 from the Pre-rRNA to Promote Formation of the Central Pseudoknot

In eukaryotes, the highly conserved U3 small nucleolar RNA (snoRNA) base-pairs to multiple sites in the pre-ribosomal RNA (pre-rRNA) to promote early cleavage and folding events. Binding of the U3 box A region to the pre-rRNA is mutually exclusive with folding of the central pseudoknot (CPK), a univ...

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Bibliographic Details
Main Authors: Sardana, Richa, Liu, Xin, Granneman, Sander, Zhu, Jieyi, Gill, Michael, Papoulas, Ophelia, Marcotte, Edward M., Tollervey, David, Correll, Carl C., Johnson, Arlen W.
Format: Online
Language:English
Published: Public Library of Science 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4340053/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4340053/

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