PARKIN ubiquitin ligase mediates resistance to intracellular pathogens
Ubiquitin-mediated targeting of intracellular bacteria to the autophagy pathway is a key innate defense mechanism against invading microbes, including the important human pathogen Mycobacterium tuberculosis. However, the ubiquitin ligases responsible for catalyzing ubiquitin chains that surround int...
Main Authors: | Manzanillo, Paolo S., Ayres, Janelle S., Watson, Robert O., Collins, Angela C., Souza, Gianne, Rae, Chris S., Schneider, David S., Nakamura, Ken, Shiloh, Michael U., Cox, Jeffery S. |
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Format: | Online |
Language: | English |
Published: |
2013
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3886920/ |
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