PARKIN ubiquitin ligase mediates resistance to intracellular pathogens

PARKIN ubiquitin ligase mediates resistance to intracellular pathogens

Ubiquitin-mediated targeting of intracellular bacteria to the autophagy pathway is a key innate defense mechanism against invading microbes, including the important human pathogen Mycobacterium tuberculosis. However, the ubiquitin ligases responsible for catalyzing ubiquitin chains that surround int...

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Bibliographic Details
Main Authors: Manzanillo, Paolo S., Ayres, Janelle S., Watson, Robert O., Collins, Angela C., Souza, Gianne, Rae, Chris S., Schneider, David S., Nakamura, Ken, Shiloh, Michael U., Cox, Jeffery S.
Format: Online
Language:English
Published: 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3886920/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3886920/

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