E3 ubiquitin ligases and their control of T cell autoreactivity

A loss of T cell tolerance underlies the development of most autoimmune diseases. The design of therapeutic strategies to reinstitute immune tolerance, however, is hampered by uncertainty regarding the molecular mechanisms involved in the inactivation of potentially autoreactive T cells. Recently, E...

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Bibliographic Details
Main Authors: Bonnevier, Jody L, Zhang, Ruan, Mueller, Daniel L
Format: Online
Language:English
Published: BioMed Central 2005
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1297590/