E3 ubiquitin ligases and their control of T cell autoreactivity
A loss of T cell tolerance underlies the development of most autoimmune diseases. The design of therapeutic strategies to reinstitute immune tolerance, however, is hampered by uncertainty regarding the molecular mechanisms involved in the inactivation of potentially autoreactive T cells. Recently, E...
Main Authors: | , , |
---|---|
Format: | Online |
Language: | English |
Published: |
BioMed Central
2005
|
Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1297590/ |