Overcoming natural replication barriers: differential helicase requirements
DNA sequences that form secondary structures or bind protein complexes are known barriers to replication and potential inducers of genome instability. In order to determine which helicases facilitate DNA replication across these barriers, we analyzed fork progression through them in wild-type and mu...
Main Authors: | Anand, Ranjith P., Shah, Kartik A., Niu, Hengyao, Sung, Patrick, Mirkin, Sergei M., Freudenreich, Catherine H. |
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Format: | Online |
Language: | English |
Published: |
Oxford University Press
2012
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3273818/ |
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