Loading mechanisms of ring helicases at replication origins
Threading of DNA through the central channel of a replicative ring helicase is known as helicase loading, and is a pivotal event during replication initiation at replication origins. Once loaded, the helicase recruits the primase through a direct protein–protein interaction to complete the initial ‘...
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| Format: | Online |
| Language: | English |
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Blackwell Publishing Ltd
2012
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3401641/ |