Viral Polymerase-Helicase Complexes Regulate Replication Fidelity To Overcome Intracellular Nucleotide Depletion

Viral Polymerase-Helicase Complexes Regulate Replication Fidelity To Overcome Intracellular Nucleotide Depletion

To date, the majority of work on RNA virus replication fidelity has focused on the viral RNA polymerase, while the potential role of other viral replicase proteins in this process is poorly understood. Previous studies used resistance to broad-spectrum RNA mutagens, such as ribavirin, to identify po...

Full description

Bibliographic Details
Main Authors: Stapleford, Kenneth A., Rozen-Gagnon, Kathryn, Das, Pratyush Kumar, Saul, Sirle, Poirier, Enzo Z., Blanc, Hervé, Vidalain, Pierre-Olivier, Merits, Andres, Vignuzzi, Marco
Format: Online
Language:English
Published: American Society for Microbiology 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4645662/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4645662/

Similar Items