Avoidance of rNMP-induced mutations via RNaseH2 and Srs2-Exo1 dependent mechanisms
Srs2 helicase is known to dismantle nucleofilaments of the Rad51 recombinase to prevent spurious recombination events1–3, 4, 5, 6 and unwind trinucleotide sequences that are prone to hairpin formation7. Here we document a new, unexpected genome maintenance role of Srs2 in the suppression of mutation...
| Main Authors: | , , , |
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| Format: | Online |
| Language: | English |
| Published: |
2014
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4140095/ |