Ciprofloxacin is an inhibitor of the Mcm2-7 replicative helicase
Most currently available small molecule inhibitors of DNA replication lack enzymatic specificity, resulting in deleterious side effects during use in cancer chemotherapy and limited experimental usefulness as mechanistic tools to study DNA replication. Towards development of targeted replication inh...
| Main Authors: | , , , , , |
|---|---|
| Format: | Online |
| Language: | English |
| Published: |
Portland Press Ltd.
2013
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3791872/ |