Pif1 helicase and Polδ promote recombination-coupled DNA synthesis via bubble migration

During DNA repair by homologous recombination (HR), DNA synthesis copies information from a template DNA molecule. Multiple DNA polymerases have been implicated in repair-specific DNA synthesis1–3, but it has remained unclear whether a DNA helicase is involved in this reaction. A good candidate is P...

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Bibliographic Details
Main Authors: Wilson, Marenda A., Kwon, YoungHo, Xu, Yuanyuan, Chung, Woo-Hyun, Chi, Peter, Niu, Hengyao, Mayle, Ryan, Chen, Xuefeng, Malkova, Anna, Sung, Patrick, Ira, Grzegorz
Format: Online
Language:English
Published: 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3915060/