The antileukaemic activity of 5-Aza-2 deoxycytidine (Aza-dC) in patients with relapsed and resistant leukaemia.
In the present study we demonstrate that Aza-dC in combination with Amsacrine has major antileukaemic properties in patients who have not already received extensive Ara-C therapy. Eight out of 11 patients in their first relapse of acute leukaemia achieved complete remission. Cross resistance between...
Main Authors: | Richel, D. J., Colly, L. P., Kluin-Nelemans, J. C., Willemze, R. |
---|---|
Format: | Online |
Language: | English |
Published: |
1991
|
Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1977302/ |
Similar Items
-
Comparison of the antileukaemic activity of 5 aza-2-deoxycytidine and arabinofuranosyl-cytosine in rats with myelocytic leukaemia.
by: Richel, D. J., et al.
Published: (1988) -
5-Aza-2′-deoxycytidine stress response and apoptosis in prostate cancer
by: Patra, Aditi, et al.
Published: (2011) -
5-Aza-2′-deoxycytidine-induced genome rearrangements are mediated by DNMT1
by: Maslov, Alexander Y., et al.
Published: (2012) -
AID downregulation is a novel function of the DNMT inhibitor 5-aza-deoxycytidine
by: Tsai, Chiou-Tsun, et al.
Published: (2013) -
Synergistic and antagonistic AML cell type-specific responses to 5-AZA-2’-Deoxycytidine and 1-H-D-Arabinofuranosylcytosine
by: Elmoneim, Abeer Abd, et al.
Published: (2014)