Comparison of the antileukaemic activity of 5 aza-2-deoxycytidine and arabinofuranosyl-cytosine in rats with myelocytic leukaemia.

Using a Brown Norway rat leukaemia model (BNML), which is a realistic model of human myelocytic leukaemia, we compared the antileukaemic activity, influence on cell cycle kinetics and effect on normal haematopoiesis of 5 aza-2-deoxycytidine (aza-dC) and arabinofuranosyl-cytosine (ara-C). The antileu...

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Bibliographic Details
Main Authors: Richel, D. J., Colly, L. P., Lurvink, E., Willemze, R.
Format: Online
Language:English
Published: Nature Publishing Group 1988
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2246862/