The epigenetic modifiers 5-aza-2'-deoxycytidine and trichostatin A influence adipocyte differentiation in human mesenchymal stem cells
Epigenetic mechanisms such as DNA methylation and histone modification are important in stem cell differentiation. Methylation is principally associated with transcriptional repression, and histone acetylation is correlated with an active chromatin state. We determined the effects of these epigeneti...
| Main Authors: | , , , , , , |
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| Format: | Online |
| Language: | English |
| Published: |
Associação Brasileira de Divulgação
Científica
2013
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3854397/ |