Sequential treatment with 5‐aza‐2′‐deoxycytidine and deacetylase inhibitors reactivates HIV‐1

Sequential treatment with 5‐aza‐2′‐deoxycytidine and deacetylase inhibitors reactivates HIV‐1

Reactivation of HIV gene expression in latently infected cells together with an efficient cART has been proposed as an adjuvant therapy aimed at eliminating/decreasing the reservoir size. Results from HIV clinical trials using deacetylase inhibitors (HDACIs) question the efficiency of these latency‐...

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Bibliographic Details
Main Authors: Bouchat, Sophie, Delacourt, Nadège, Kula, Anna, Darcis, Gilles, Van Driessche, Benoit, Corazza, Francis, Gatot, Jean‐Stéphane, Melard, Adeline, Vanhulle, Caroline, Kabeya, Kabamba, Pardons, Marion, Avettand‐Fenoel, Véronique, Clumeck, Nathan, De Wit, Stéphane, Rohr, Olivier, Rouzioux, Christine, Van Lint, Carine
Format: Online
Language:English
Published: John Wiley and Sons Inc. 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4734845/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4734845/

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