DNA demethylation caused by 5-Aza-2′-deoxycytidine induces mitotic alterations and aneuploidy
Aneuploidy, the unbalanced number of chromosomes in a cell, is considered a prevalent form of genetic instability and is largely acknowledged as a condition implicated in tumorigenesis. Epigenetic alterations like DNA hypomethylation have been correlated with cancer initiation/progression. Furthermo...
| Main Authors: | , , , , |
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| Format: | Online |
| Language: | English |
| Published: |
Impact Journals LLC
2016
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4826165/ |