DNA deaminases induce break-associated mutation showers with implication of APOBEC3B and 3A in breast cancer kataegis

by Taylor, Benjamin JM, Nik-Zainal, Serena, Wu, Yee Ling, Stebbings, Lucy A, Raine, Keiran, Campbell, Peter J, Rada, Cristina, Stratton, Michael R, Neuberger, Michael S
Published 2013

Somatic structural rearrangements in genetically engineered mouse mammary tumors

by Varela, Ignacio, Klijn, Christiaan, Stephens, Phillip J, Mudie, Laura J, Stebbings, Lucy, Galappaththige, Danushka, van der Gulden, Hanneke, Schut, Eva, Klarenbeek, Sjoerd, Campbell, Peter J, Wessels, Lodewyk FA, Stratton, Michael R, Jonkers, Jos, Futreal, P Andrew, Adams, David J
Published 2010

Massively Parallel Sequencing Reveals the Complex Structure of an Irradiated Human Chromosome on a Mouse Background in the Tc1 Model of Down Syndrome

by Gribble, Susan M., Wiseman, Frances K., Clayton, Stephen, Prigmore, Elena, Langley, Elizabeth, Yang, Fengtang, Maguire, Sean, Fu, Beiyuan, Rajan, Diana, Sheppard, Olivia, Scott, Carol, Hauser, Heidi, Stephens, Philip J., Stebbings, Lucy A., Ng, Bee Ling, Fitzgerald, Tomas, Quail, Michael A., Banerjee, Ruby, Rothkamm, Kai, Tybulewicz, Victor L. J., Fisher, Elizabeth M. C., Carter, Nigel P.
Published 2013

Single-cell paired-end genome sequencing reveals structural variation per cell cycle

by Voet, Thierry, Kumar, Parveen, Van Loo, Peter, Cooke, Susanna L., Marshall, John, Lin, Meng-Lay, Zamani Esteki, Masoud, Van der Aa, Niels, Mateiu, Ligia, McBride, David J., Bignell, Graham R., McLaren, Stuart, Teague, Jon, Butler, Adam, Raine, Keiran, Stebbings, Lucy A., Quail, Michael A., D’Hooghe, Thomas, Moreau, Yves, Futreal, P. Andrew, Stratton, Michael R., Vermeesch, Joris R., Campbell, Peter J.
Published 2013

The patterns and dynamics of genomic instability in metastatic pancreatic cancer

by Campbell, Peter J, Yachida, Shinichi, Mudie, Laura J, Stephens, Philip J, Pleasance, Erin D, Stebbings, Lucy A, Morsberger, Laura A, Latimer, Calli, McLaren, Stuart, Lin, Meng-Lay, McBride, David J, Varela, Ignacio, Nik-Zainal, Serena A, Leroy, Catherine, Jia, Mingming, Menzies, Andrew, Butler, Adam P, Teague, Jon W, Griffin, Constance A, Burton, John, Swerdlow, Harold, Quail, Michael A, Stratton, Michael R, Iacobuzio-Donahue, Christine, Futreal, P Andrew
Published 2010

Mutational signatures of ionizing radiation in second malignancies

by Behjati, Sam, Gundem, Gunes, Wedge, David C., Roberts, Nicola D., Tarpey, Patrick S., Cooke, Susanna L., Van Loo, Peter, Alexandrov, Ludmil B., Ramakrishna, Manasa, Davies, Helen, Nik-Zainal, Serena, Hardy, Claire, Latimer, Calli, Raine, Keiran M., Stebbings, Lucy, Menzies, Andy, Jones, David, Shepherd, Rebecca, Butler, Adam P., Teague, Jon W., Jorgensen, Mette, Khatri, Bhavisha, Pillay, Nischalan, Shlien, Adam, Futreal, P. Andrew, Badie, Christophe, McDermott, Ultan, Bova, G. Steven, Richardson, Andrea L., Flanagan, Adrienne M., Stratton, Michael R., Campbell, Peter J.
Published 2016

Massive Genomic Rearrangement Acquired in a Single Catastrophic Event during Cancer Development

by Stephens, Philip J., Greenman, Chris D., Fu, Beiyuan, Yang, Fengtang, Bignell, Graham R., Mudie, Laura J., Pleasance, Erin D., Lau, King Wai, Beare, David, Stebbings, Lucy A., McLaren, Stuart, Lin, Meng-Lay, McBride, David J., Varela, Ignacio, Nik-Zainal, Serena, Leroy, Catherine, Jia, Mingming, Menzies, Andrew, Butler, Adam P., Teague, Jon W., Quail, Michael A., Burton, John, Swerdlow, Harold, Carter, Nigel P., Morsberger, Laura A., Iacobuzio-Donahue, Christine, Follows, George A., Green, Anthony R., Flanagan, Adrienne M., Stratton, Michael R., Futreal, P. Andrew, Campbell, Peter J.
Published 2011

COMPLEX LANDSCAPES OF SOMATIC REARRANGEMENT IN HUMAN BREAST CANCER GENOMES

by Stephens, Philip J, McBride, David J, Lin, Meng-Lay, Varela, Ignacio, Pleasance, Erin D, Simpson, Jared T, Stebbings, Lucy A, Leroy, Catherine, Edkins, Sarah, Mudie, Laura J, Greenman, Chris D, Jia, Mingming, Latimer, Calli, Teague, Jon W, Lau, King Wai, Burton, John, Quail, Michael A, Swerdlow, Harold, Churcher, Carol, Natrajan, Rachael, Sieuwerts, Anieta M, Martens, John WM, Silver, Daniel P, Langerod, Anita, Russnes, Hege EG, Foekens, John A, Reis-Filho, Jorge S, van ’t Veer, Laura, Richardson, Andrea L, Børreson-Dale, Anne-Lise, Campbell, Peter J, Futreal, P Andrew, Stratton, Michael R
Published 2009

Mutational Processes Molding the Genomes of 21 Breast Cancers

by Nik-Zainal, Serena, Alexandrov, Ludmil B., Wedge, David C., Van Loo, Peter, Greenman, Christopher D., Raine, Keiran, Jones, David, Hinton, Jonathan, Marshall, John, Stebbings, Lucy A., Menzies, Andrew, Martin, Sancha, Leung, Kenric, Chen, Lina, Leroy, Catherine, Ramakrishna, Manasa, Rance, Richard, Lau, King Wai, Mudie, Laura J., Varela, Ignacio, McBride, David J., Bignell, Graham R., Cooke, Susanna L., Shlien, Adam, Gamble, John, Whitmore, Ian, Maddison, Mark, Tarpey, Patrick S., Davies, Helen R., Papaemmanuil, Elli, Stephens, Philip J., McLaren, Stuart, Butler, Adam P., Teague, Jon W., Jönsson, Göran, Garber, Judy E., Silver, Daniel, Miron, Penelope, Fatima, Aquila, Boyault, Sandrine, Langerød, Anita, Tutt, Andrew, Martens, John W.M., Aparicio, Samuel A.J.R., Borg, Åke, Salomon, Anne Vincent, Thomas, Gilles, Børresen-Dale, Anne-Lise, Richardson, Andrea L., Neuberger, Michael S., Futreal, P. Andrew, Campbell, Peter J., Stratton, Michael R.
Published 2012

The Life History of 21 Breast Cancers

by Nik-Zainal, Serena, Van Loo, Peter, Wedge, David C., Alexandrov, Ludmil B., Greenman, Christopher D., Lau, King Wai, Raine, Keiran, Jones, David, Marshall, John, Ramakrishna, Manasa, Shlien, Adam, Cooke, Susanna L., Hinton, Jonathan, Menzies, Andrew, Stebbings, Lucy A., Leroy, Catherine, Jia, Mingming, Rance, Richard, Mudie, Laura J., Gamble, Stephen J., Stephens, Philip J., McLaren, Stuart, Tarpey, Patrick S., Papaemmanuil, Elli, Davies, Helen R., Varela, Ignacio, McBride, David J., Bignell, Graham R., Leung, Kenric, Butler, Adam P., Teague, Jon W., Martin, Sancha, Jönsson, Goran, Mariani, Odette, Boyault, Sandrine, Miron, Penelope, Fatima, Aquila, Langerød, Anita, Aparicio, Samuel A.J.R., Tutt, Andrew, Sieuwerts, Anieta M., Borg, Åke, Thomas, Gilles, Salomon, Anne Vincent, Richardson, Andrea L., Børresen-Dale, Anne-Lise, Futreal, P. Andrew, Stratton, Michael R., Campbell, Peter J.
Published 2012

Analysis of the Genetic Phylogeny of Multifocal Prostate Cancer Identifies Multiple Independent Clonal Expansions in Neoplastic and Morphologically Normal Prostate Tissue

by Cooper, Colin S, Eeles, Rosalind, Wedge, David C, Van Loo, Peter, Gundem, Gunes, Alexandrov, Ludmil B, Kremeyer, Barbara, Butler, Adam, Lynch, Andrew G, Camacho, Niedzica, Massie, Charlie E, Kay, Jonathan, Luxton, Hayley J, Edwards, Sandra, Kote-Jarai, ZSofia, Dennis, Nening, Merson, Sue, Leongamornlert, Daniel, Zamora, Jorge, Corbishley, Cathy, Thomas, Sarah, Nik-Zainal, Serena, O’Meara, Sarah, Matthews, Lucy, Clark, Jeremy, Hurst, Rachel, Mithen, Richard, Bristow, Robert G, Boutros, Paul C, Fraser, Michael, Cooke, Susanna, Raine, Keiran, Jones, David, Menzies, Andrew, Stebbings, Lucy, Hinton, Jon, Teague, Jon, McLaren, Stuart, Mudie, Laura, Hardy, Claire, Anderson, Elizabeth, Joseph, Olivia, Goody, Victoria, Robinson, Ben, Maddison, Mark, Gamble, Stephen, Greenman, Christopher, Berney, Dan, Hazell, Steven, Livni, Naomi, Fisher, Cyril, Ogden, Christopher, Kumar, Pardeep, Thompson, Alan, Woodhouse, Christopher, Nicol, David, Mayer, Erik, Dudderidge, Tim, Shah, Nimish C, Gnanapragasam, Vincent, Voet, Thierry, Campbell, Peter, Futreal, Andrew, Easton, Douglas, Warren, Anne Y, Foster, Christopher S, Stratton, Michael R, Whitaker, Hayley C, McDermott, Ultan, Brewer, Daniel S, Neal, David E
Published 2015

Landscape of somatic mutations in 560 breast cancer whole genome sequences

by Nik-Zainal, Serena, Davies, Helen, Staaf, Johan, Ramakrishna, Manasa, Glodzik, Dominik, Zou, Xueqing, Martincorena, Inigo, Alexandrov, Ludmil B., Martin, Sancha, Wedge, David C., Van Loo, Peter, Ju, Young Seok, Smid, Marcel, Brinkman, Arie B, Morganella, Sandro, Aure, Miriam R., Lingjærde, Ole Christian, Langerød, Anita, Ringnér, Markus, Ahn, Sung-Min, Boyault, Sandrine, Brock, Jane E., Broeks, Annegien, Butler, Adam, Desmedt, Christine, Dirix, Luc, Dronov, Serge, Fatima, Aquila, Foekens, John A., Gerstung, Moritz, Hooijer, Gerrit KJ, Jang, Se Jin, Jones, David R., Kim, Hyung-Yong, King, Tari A., Krishnamurthy, Savitri, Lee, Hee Jin, Lee, Jeong-Yeon, Li, Yilong, McLaren, Stuart, Menzies, Andrew, Mustonen, Ville, O’Meara, Sarah, Pauporté, Iris, Pivot, Xavier, Purdie, Colin A., Raine, Keiran, Ramakrishnan, Kamna, Rodríguez-González, F. Germán, Romieu, Gilles, Sieuwerts, Anieta M., Simpson, Peter T, Shepherd, Rebecca, Stebbings, Lucy, Stefansson, Olafur A, Teague, Jon, Tommasi, Stefania, Treilleux, Isabelle, Van den Eynden, Gert G., Vermeulen, Peter, Vincent-Salomon, Anne, Yates, Lucy, Caldas, Carlos, van’t Veer, Laura, Tutt, Andrew, Knappskog, Stian, Tan, Benita Kiat Tee, Jonkers, Jos, Borg, Åke, Ueno, Naoto T, Sotiriou, Christos, Viari, Alain, Futreal, P. Andrew, Campbell, Peter J, Span, Paul N., Van Laere, Steven, Lakhani, Sunil R, Eyfjord, Jorunn E., Thompson, Alastair M., Birney, Ewan, Stunnenberg, Hendrik G, van de Vijver, Marc J, Martens, John W.M., Børresen-Dale, Anne-Lise, Richardson, Andrea L., Kong, Gu, Thomas, Gilles, Stratton, Michael R.
Published 2016

A comprehensive assessment of somatic mutation detection in cancer using whole-genome sequencing

by Alioto, Tyler S., Buchhalter, Ivo, Derdak, Sophia, Hutter, Barbara, Eldridge, Matthew D., Hovig, Eivind, Heisler, Lawrence E., Beck, Timothy A., Simpson, Jared T., Tonon, Laurie, Sertier, Anne-Sophie, Patch, Ann-Marie, Jäger, Natalie, Ginsbach, Philip, Drews, Ruben, Paramasivam, Nagarajan, Kabbe, Rolf, Chotewutmontri, Sasithorn, Diessl, Nicolle, Previti, Christopher, Schmidt, Sabine, Brors, Benedikt, Feuerbach, Lars, Heinold, Michael, Gröbner, Susanne, Korshunov, Andrey, Tarpey, Patrick S., Butler, Adam P., Hinton, Jonathan, Jones, David, Menzies, Andrew, Raine, Keiran, Shepherd, Rebecca, Stebbings, Lucy, Teague, Jon W., Ribeca, Paolo, Giner, Francesc Castro, Beltran, Sergi, Raineri, Emanuele, Dabad, Marc, Heath, Simon C., Gut, Marta, Denroche, Robert E., Harding, Nicholas J., Yamaguchi, Takafumi N., Fujimoto, Akihiro, Nakagawa, Hidewaki, Quesada, Víctor, Valdés-Mas, Rafael, Nakken, Sigve, Vodák, Daniel, Bower, Lawrence, Lynch, Andrew G., Anderson, Charlotte L., Waddell, Nicola, Pearson, John V., Grimmond, Sean M., Peto, Myron, Spellman, Paul, He, Minghui, Kandoth, Cyriac, Lee, Semin, Zhang, John, Létourneau, Louis, Ma, Singer, Seth, Sahil, Torrents, David, Xi, Liu, Wheeler, David A., López-Otín, Carlos, Campo, Elías, Campbell, Peter J., Boutros, Paul C., Puente, Xose S., Gerhard, Daniela S., Pfister, Stefan M., McPherson, John D., Hudson, Thomas J., Schlesner, Matthias, Lichter, Peter, Eils, Roland, Jones, David T. W., Gut, Ivo G.
Published 2015