MEK inhibition as a strategy for targeting residual breast cancer cells with low DUSP4 expression

by Rottenberg, Sven, Jonkers, Jos
Published 2012

Rapid validation of cancer genes in chimeras derived from established genetically engineered mouse models

by Huijbers, Ivo J, Krimpenfort, Paul, Berns, Anton, Jonkers, Jos
Published 2011

Identification of cancer genes using a statistical framework for multiexperiment analysis of nondiscretized array CGH data

by Klijn, Christiaan, Holstege, Henne, de Ridder, Jeroen, Liu, Xiaoling, Reinders, Marcel, Jonkers, Jos, Wessels, Lodewyk
Published 2008

BRCA1 and CtIP promote alternative non-homologous end-joining at uncapped telomeres

by Badie, Sophie, Carlos, Ana Rita, Folio, Cecilia, Okamoto, Keiji, Bouwman, Peter, Jonkers, Jos, Tarsounas, Madalena
Published 2015

EZN-2208 (PEG-SN38) Overcomes ABCG2-Mediated Topotecan Resistance in BRCA1-Deficient Mouse Mammary Tumors

by Zander, Serge A. L., Sol, Wendy, Greenberger, Lee, Zhang, Yixian, van Tellingen, Olaf, Jonkers, Jos, Borst, Piet, Rottenberg, Sven
Published 2012

Mammary-specific inactivation of E-cadherin and p53 impairs functional gland development and leads to pleomorphic invasive lobular carcinoma in mice

by Derksen, Patrick W. B., Braumuller, Tanya M., van der Burg, Eline, Hornsveld, Marten, Mesman, Elly, Wesseling, Jelle, Krimpenfort, Paul, Jonkers, Jos
Published 2011

Use of a Single Hybrid Imaging Agent for Integration of Target Validation with In Vivo and Ex Vivo Imaging of Mouse Tumor Lesions Resembling Human DCIS

by Buckle, Tessa, Kuil, Joeri, van den Berg, Nynke S., Bunschoten, Anton, Lamb, Hildo J., Yuan, Hushan, Josephson, Lee, Jonkers, Jos, Borowsky, Alexander D., van Leeuwen, Fijs W. B.
Published 2013

p120-Catenin Is Critical for the Development of Invasive Lobular Carcinoma in Mice

by Tenhagen, Milou, Klarenbeek, Sjoerd, Braumuller, Tanya M., Hofmann, Ilse, van der Groep, Petra, ter Hoeve, Natalie, van der Wall, Elsken, Jonkers, Jos, Derksen, Patrick W. B.
Published 2016

Cooperation between BRCA1 and vitamin D is critical for histone acetylation of the p21waf1 promoter and for growth inhibition of breast cancer cells and cancer stem-like cells

by Pickholtz, Itay, Saadyan, Shira, Keshet, Gilmor I., Wang, Victor S., Cohen, Rachel, Bouwman, Peter, Jonkers, Jos, Byers, Stephen W., Papa, Moshe Z., Yarden, Ronit I.
Published 2014

Lack of Genomic Heterogeneity at High-Resolution aCGH between Primary Breast Cancers and Their Paired Lymph Node Metastases

by Vollebergh, Marieke A., Klijn, Christiaan, Schouten, Philip C., Wesseling, Jelle, Israeli, Danielle, Ylstra, Bauke, Wessels, Lodewyk F.A., Jonkers, Jos, Linn, Sabine C.
Published 2014

Somatic structural rearrangements in genetically engineered mouse mammary tumors

by Varela, Ignacio, Klijn, Christiaan, Stephens, Phillip J, Mudie, Laura J, Stebbings, Lucy, Galappaththige, Danushka, van der Gulden, Hanneke, Schut, Eva, Klarenbeek, Sjoerd, Campbell, Peter J, Wessels, Lodewyk FA, Stratton, Michael R, Jonkers, Jos, Futreal, P Andrew, Adams, David J
Published 2010

Computational identification of insertional mutagenesis targets for cancer gene discovery

by de Jong, Johann, de Ridder, Jeroen, van der Weyden, Louise, Sun, Ning, van Uitert, Miranda, Berns, Anton, van Lohuizen, Maarten, Jonkers, Jos, Adams, David J., Wessels, Lodewyk F. A.
Published 2011

Human and mouse oligonucleotide-based array CGH

by van den IJssel, Paul, Tijssen, Marianne, Chin, Suet-Feung, Eijk, Paul, Carvalho, Beatriz, Hopmans, Erik, Holstege, Henne, Bangarusamy, Dhinoth Kumar, Jonkers, Jos, Meijer, Gerrit A., Caldas, Carlos, Ylstra, Bauke
Published 2005

Defined lipid analogues induce transient channels to facilitate drug-membrane traversal and circumvent cancer therapy resistance

by van Hell, Albert J., Melo, Manuel N., van Blitterswijk, Wim J., Gueth, Dayana M., Braumuller, Tanya M., Pedrosa, Lilia R. C., Song, Ji-Ying, Marrink, Siewert J., Koning, Gerben A., Jonkers, Jos, Verheij, Marcel
Published 2013

Analysis of Tumor Heterogeneity and Cancer Gene Networks Using Deep Sequencing of MMTV-Induced Mouse Mammary Tumors

by Klijn, Christiaan, Koudijs, Marco J., Kool, Jaap, ten Hoeve, Jelle, Boer, Mandy, de Moes, Joost, Akhtar, Waseem, van Miltenburg, Martine, Vendel-Zwaagstra, Annabel, Reinders, Marcel J. T., Adams, David J., van Lohuizen, Maarten, Hilkens, John, Wessels, Lodewyk F. A., Jonkers, Jos
Published 2013

Genomic patterns resembling BRCA1- and BRCA2-mutated breast cancers predict benefit of intensified carboplatin-based chemotherapy

by Vollebergh, Marieke A, Lips, Esther H, Nederlof, Petra M, Wessels, Lodewyk FA, Wesseling, Jelle, vd Vijver, Marc J, de Vries, Elisabeth GE, van Tinteren, Harm, Jonkers, Jos, Hauptmann, Michael, Rodenhuis, Sjoerd, Linn, Sabine C
Published 2014

Rapid target gene validation in complex cancer mouse models using re-derived embryonic stem cells

by Huijbers, Ivo J, Bin Ali, Rahmen, Pritchard, Colin, Cozijnsen, Miranda, Kwon, Min-Chul, Proost, Natalie, Song, Ji-Ying, Vries, Hilda, Badhai, Jitendra, Sutherland, Kate, Krimpenfort, Paul, Michalak, Ewa M, Jonkers, Jos, Berns, Anton
Published 2014

Spontaneous bone metastases in a preclinical orthotopic model of invasive lobular carcinoma; the effect of pharmacological targeting TGFβ receptor I kinase

by Buijs, Jeroen T, Matula, Kasia M, Cheung, Henry, Kruithof-de Julio, Marianna, van der Mark, Maaike H, Snoeks, Thomas J, Cohen, Ron, Corver, Willem E, Mohammad, Khalid S, Jonkers, Jos, Guise, Theresa A, van der Pluijm, Gabri
Published 2015

PTEN Loss in E-Cadherin-Deficient Mouse Mammary Epithelial Cells Rescues Apoptosis and Results in Development of Classical Invasive Lobular Carcinoma

by Boelens, Mirjam C., Nethe, Micha, Klarenbeek, Sjoerd, de Ruiter, Julian R., Schut, Eva, Bonzanni, Nicola, Zeeman, Amber L., Wientjens, Ellen, van der Burg, Eline, Wessels, Lodewyk, van Amerongen, Renée, Jonkers, Jos
Published 2016

IL17-producing γδ T cells and neutrophils conspire to promote breast cancer metastasis

by Coffelt, Seth B., Kersten, Kelly, Doornebal, Chris W., Weiden, Jorieke, Vrijland, Kim, Hau, Cheei-Sing, Verstegen, Niels J.M., Ciampricotti, Metamia, Hawinkels, Lukas J.A.C., Jonkers, Jos, de Visser, Karin E.
Published 2015