A novel independence test for somatic alterations in cancer shows that biology drives mutual exclusivity but chance explains most co-occurrence

by Canisius, Sander, Martens, John W. M., Wessels, Lodewyk F. A.
Published 2016

Stromal cells promote anti-estrogen resistance of breast cancer cells through an insulin-like growth factor binding protein 5 (IGFBP5)/B-cell leukemia/lymphoma 3 (Bcl-3) axis

by Leyh, Benjamin, Dittmer, Angela, Lange, Theresia, Martens, John W. M., Dittmer, Jürgen
Published 2015

Genomic profiling of CHEK2*1100delC-mutated breast carcinomas

by Massink, Maarten P. G., Kooi, Irsan E., Martens, John W. M., Waisfisz, Quinten, Meijers-Heijboer, Hanne
Published 2015

Proteomics Pipeline for Biomarker Discovery of Laser Capture Microdissected Breast Cancer Tissue

by Liu, Ning Qing, Braakman, René B. H., Stingl, Christoph, Luider, Theo M., Martens, John W. M., Foekens, John A., Umar, Arzu
Published 2012

Mitochondrial DNA content in breast cancer: Impact on in vitro and in vivo phenotype and patient prognosis

by Weerts, Marjolein J.A., Sieuwerts, Anieta M., Smid, Marcel, Look, Maxime P., Foekens, John A., Sleijfer, Stefan, Martens, John W.M.
Published 2016

The 29.5 kb APOBEC3B Deletion Polymorphism Is Not Associated with Clinical Outcome of Breast Cancer

by Liu, Jingjing, Sieuwerts, Anieta M., Look, Maxime P., van der Vlugt-Daane, Michelle, Meijer-van Gelder, Marion E., Foekens, John A., Hollestelle, Antoinette, Martens, John W. M.
Published 2016

Global proteomic characterization of microdissected estrogen receptor positive breast tumors

by De Marchi, Tommaso, Liu, Ning Qing, Sting, Christoph, Smid, Marcel, Tjoa, Mila, Braakman, René B.H., Luider, Theo M., Foekens, John A., Martens, John W.M., Umar, Arzu
Published 2015

Sensitivity to systemic therapy for metastatic breast cancer in CHEK2 1100delC mutation carriers

by Kriege, Mieke, Jager, Agnes, Hollestelle, Antoinette, Berns, Els M. J. J., Blom, Jannet, Meijer-van Gelder, Marion E., Sieuwerts, Anieta M., van den Ouweland, Ans, Collée, J. Margriet, Kroep, Judith R., Martens, John W. M., Hooning, Maartje J., Seynaeve, Caroline
Published 2015

Prognostic Impact of HER2 and ER Status of Circulating Tumor Cells in Metastatic Breast Cancer Patients with a HER2-Negative Primary Tumor1

by Beije, Nick, Onstenk, Wendy, Kraan, Jaco, Sieuwerts, Anieta M., Hamberg, Paul, Dirix, Luc Y., Brouwer, Anja, de Jongh, Felix E., Jager, Agnes, Seynaeve, Caroline M., Van, Ngoc M., Foekens, John A., Martens, John W.M., Sleijfer, Stefan
Published 2016

Understanding drugs in breast cancer through drug sensitivity screening

by Uhr, Katharina, Prager-van der Smissen, Wendy J. C., Heine, Anouk A. J., Ozturk, Bahar, Smid, Marcel, Göhlmann, Hinrich W. H., Jager, Agnes, Foekens, John A., Martens, John W. M.
Published 2015

A Method to Correlate mRNA Expression Datasets Obtained from Fresh Frozen and Formalin-Fixed, Paraffin-Embedded Tissue Samples: A Matter of Thresholds

by Mustafa, Dana A. M., Sieuwerts, Anieta M., Smid, Marcel, de Weerd, Vania, van der Weiden, Marcel, Meijer - van Gelder, Marion E., Martens, John W. M., Foekens, John A., Kros, Johan M.
Published 2015

Elevated APOBEC3B Correlates with Poor Outcomes for Estrogen-Receptor-Positive Breast Cancers

by Sieuwerts, Anieta M., Willis, Scooter, Burns, Michael B., Look, Maxime P., Gelder, Marion E. Meijer-Van, Schlicker, Andreas, Heideman, Marinus R., Jacobs, Heinz, Wessels, Lodewyk, Leyland-Jones, Brian, Gray, Kathryn P., Foekens, John A., Harris, Reuben S., Martens, John W. M.
Published 2014

DC-SCRIPT is a novel regulator of the tumor suppressor gene CDKN2B and induces cell cycle arrest in ERα-positive breast cancer cells

by Ansems, Marleen, Søndergaard, Jonas Nørskov, Sieuwerts, Anieta M., Looman, Maaike W. G., Smid, Marcel, de Graaf, Annemarie M. A., de Weerd, Vanja, Zuidscherwoude, Malou, Foekens, John A., Martens, John W. M., Adema, Gosse J.
Published 2015

Comparative Proteome Analysis Revealing an 11-Protein Signature for Aggressive Triple-Negative Breast Cancer

by Liu, Ning Qing, Stingl, Christoph, Look, Maxime P., Smid, Marcel, Braakman, René B.H., De Marchi, Tommaso, Sieuwerts, Anieta M., Span, Paul N., Sweep, Fred C.G.J., Linderholm, Barbro K., Mangia, Anita, Paradiso, Angelo, Dirix, Luc Y., Van Laere, Steven J., Luider, Theo M., Martens, John W.M., Foekens, John A., Umar, Arzu
Published 2014

Cell-free DNA mutations as biomarkers in breast cancer patients receiving tamoxifen

by Jansen, Maurice P.H.M., Martens, John W.M., Helmijr, Jean C.A., Beaufort, Corine M., van Marion, Ronald, Krol, Niels M.G., Monkhorst, Kim, Trapman-Jansen, Anita M.A.C., Meijer-van Gelder, Marion E., Weerts, Marjolein J.A., Ramirez-Ardila, Diana E., Jan Dubbink, Hendrikus, Foekens, John A., Sleijfer, Stefan, Berns, Els M.J.J.
Published 2016

Prognostic significance of nuclear expression of UMP-CMP kinase in triple negative breast cancer patients

by Liu, Ning Qing, De Marchi, Tommaso, Timmermans, Annemieke, Trapman-Jansen, Anita M. A. C., Foekens, Renée, Look, Maxime P., Smid, Marcel, van Deurzen, Carolien H. M., Span, Paul N., Sweep, Fred C. G. J., Brask, Julie Benedicte, Timmermans-Wielenga, Vera, Foekens, John A., Martens, John W. M., Umar, Arzu
Published 2016

The DNA cytosine deaminase APOBEC3B promotes tamoxifen resistance in ER-positive breast cancer

by Law, Emily K., Sieuwerts, Anieta M., LaPara, Kelly, Leonard, Brandon, Starrett, Gabriel J., Molan, Amy M., Temiz, Nuri A., Vogel, Rachel Isaksson, Meijer-van Gelder, Marion E., Sweep, Fred C. G. J., Span, Paul N., Foekens, John A., Martens, John W. M., Yee, Douglas, Harris, Reuben S.
Published 2016

An 8-gene mRNA expression profile in circulating tumor cells predicts response to aromatase inhibitors in metastatic breast cancer patients

by Reijm, Esther A., Sieuwerts, Anieta M., Smid, Marcel, Vries, Joan Bolt-de, Mostert, Bianca, Onstenk, Wendy, Peeters, Dieter, Dirix, Luc Y., Seynaeve, Caroline M., Jager, Agnes, de Jongh, Felix E., Hamberg, Paul, van Galen, Anne, Kraan, Jaco, Jansen, Maurice P. H. M., Gratama, Jan W., Foekens, John A., Martens, John W. M., Berns, Els M. J. J., Sleijfer, Stefan
Published 2016

Ferritin Heavy Chain in Triple Negative Breast Cancer: A Favorable Prognostic Marker that Relates to a Cluster of Differentiation 8 Positive (CD8+) Effector T-cell Response*

by Liu, Ning Qing, De Marchi, Tommaso, Timmermans, Annemieke M., Beekhof, Robin, Trapman-Jansen, Anita M.A.C., Foekens, Renée, Look, Maxime P., van Deurzen, Carolien H. M., Span, Paul N., Sweep, Fred C.G.J., Brask, Julie Benedicte, Timmermans-Wielenga, Vera, Debets, Reno, Martens, John W. M., Foekens, John A., Umar, Arzu
Published 2014

Recurrent HOXB13 mutations in the Dutch population do not associate with increased breast cancer risk

by Liu, Jingjing, Prager–van der Smissen, Wendy J. C., Schmidt, Marjanka K., Collée, J. Margriet, Cornelissen, Sten, Lamping, Roy, Nieuwlaat, Anja, Foekens, John A., Hooning, Maartje J., Verhoef, Senno, van den Ouweland, Ans M. W., Hogervorst, Frans B. L., Martens, John W. M., Hollestelle, Antoinette
Published 2016