Telomere length predicts progression and overall survival in chronic lymphocytic leukemia: data from the UK LRF CLL4 trial

Telomere length predicts progression and overall survival in chronic lymphocytic leukemia: data from the UK LRF CLL4 trial

Bibliographic Details
Main Authors:	Strefford, JC, Kadalayil, L, Forster, J, Rose-Zerilli, MJJ, Parker, A, Lin, TT, Heppel, N, Norris, K, Gardiner, A, Davies, Z, Gonzalez de Castro, D, Else, M, Steele, AJ, Parker, H, Stankovic, T, Pepper, C, Fegan, C, Baird, D, Collins, A, Catovsky, D, Oscier, DG
Format:	Online
Language:	English
Published:	2015
Online Access:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4676082/

Similar Items

The morphology of CLL revisited: the clinical significance of prolymphocytes and correlations with prognostic/molecular markers in the LRF CLL4 trial
by: Oscier, David, et al.
Published: (2016)

The long‐term outcome of patients in the LRF CLL4 trial: the effect of salvage treatment and biological markers in those surviving 10 years
by: Else, Monica, et al.
Published: (2015)

The use of individualized tumor response testing in treatment selection: second randomization results from the LRF CLL4 trial and the predictive value of the test at trial entry
by: Matutes, E, et al.
Published: (2013)

Longitudinal copy number, whole exome and targeted deep sequencing of 'good risk' IGHV-mutated CLL patients with progressive disease
by: Rose-Zerilli, M J J, et al.
Published: (2016)

Cross-talk between DNA methylation and active histone modifications regulates aberrant expression of ZAP70 in CLL
by: Amin, Shilu, et al.
Published: (2012)

A CD21 low phenotype, with no evidence of autoantibodies to complement proteins, is consistent with a poor prognosis in CLL
by: Nichols, Eva-Maria, et al.
Published: (2015)

LRF assissted mapping and obstacle avoidance for hexapod robot Comet
by: Mohd Razali, Daud
Published: (2012)

The Oncogene LRF Stimulates Proliferation of Mesenchymal Stem Cells and Inhibits Their Chondrogenic Differentiation
by: Yik, Jasper H.N., et al.
Published: (2013)

Whole Exome Sequencing Identifies Novel Recurrently Mutated Genes in Patients with Splenic Marginal Zone Lymphoma
by: Parry, Marina, et al.
Published: (2013)

Double IGHV DNA gene rearrangements in CLL: influence of mixed-mutated and -unmutated rearrangements on outcomes in CLL
by: Heyman, B, et al.
Published: (2016)

Stimulation by CLL cells in mixed lymphocyte culture (MLC).
by: Jones, E. H., et al.
Published: (1981)

Leptomeningeal involvement in CLL
by: Chantepie, Sylvain P., et al.
Published: (2014)

Population Pharmacokinetics of Obinutuzumab (GA101) in Chronic Lymphocytic Leukemia (CLL) and Non-Hodgkin's Lymphoma and Exposure–Response in CLL
by: Gibiansky, E, et al.
Published: (2014)

The Hsp90 inhibitor NVP-AUY922-AG inhibits NF-κB signaling, overcomes microenvironmental cytoprotection and is highly synergistic with fludarabine in primary CLL cells
by: Walsby, Elisabeth, et al.
Published: (2012)

Phenotypic heterogeneity in IGHV-mutated CLL patients has prognostic impact and identifies a subset with increased sensitivity to BTK and PI3Kδ inhibition
by: Pepper, C, et al.
Published: (2015)

Immunotherapy in Chronic Lymphocytic Leukaemia (CLL)
by: Freeman, Ciara L., et al.
Published: (2016)

Lrf suppresses prostate cancer through repression of a Sox9-dependent pathway for cellular senescence bypass and tumor invasion
by: Wang, Guocan, et al.
Published: (2013)

Metabolic plasticity in CLL: adaptation to the hypoxic niche
by: Koczula, K M, et al.
Published: (2016)

The Dohner fluorescence in situ hybridization prognostic classification of chronic lymphocytic leukaemia (CLL): the CLL Research Consortium experience
by: Van Dyke, Daniel L., et al.
Published: (2016)

3D Image Construction Using Single LRF Hokuyo URG-04LX
by: Hendriyawan, Achmad, et al.
Published: (2014)

LRF maintains genome integrity by regulating the non-homologous end joining pathway of DNA repair
by: Liu, Xue-Song, et al.
Published: (2015)

A ThPOK-LRF transcriptional node maintains the integrity and effector potential of post-thymic CD4+ T cells
by: Vacchio, Melanie S., et al.
Published: (2014)

Generation of Functional CLL-Specific Cord Blood CTL Using CD40-Ligated CLL APC
by: Decker, William K., et al.
Published: (2012)

Factors involved in CLL pathogenesis and cell survival are disrupted by differentiation of CLL B-cells into antibody-secreting cells
by: Ghamlouch, Hussein, et al.
Published: (2015)

Comparison of outcome of patients with CLL who are referred or nonreferred to a specialized CLL clinic: a Canadian population‐based study
by: Beiggi, Sara, et al.
Published: (2016)

Mutations driving CLL and their evolution in progression and relapse
by: Landau, Dan A., et al.
Published: (2015)

Mechanisms and consequences of the loss of PHLPP1 phosphatase in chronic lymphocytic leukemia (CLL)
by: O'Hayre, M, et al.
Published: (2012)

Experiences in the design and implementation of phase II trials in CLL
by: Cohen, Dena R, et al.
Published: (2011)

Immunological aspects in chronic lymphocytic leukemia (CLL) development
by: García-Muñoz, Ricardo, et al.
Published: (2012)

Adult T-cell leukemia/lymphoma with CLL-like morphology
by: Kim, Do-Hoon, et al.
Published: (2011)

Umbelliprenin Induces Apoptosis in CLL Cell Lines
by: Ziai, Seyed Ali, et al.
Published: (2012)

The Effect of Osmotic Shock on Release of Bacterial Proteins and on Active Transport
by: Heppel, Leon A.
Published: (1969)

Proceedings: Methods for the study and cell differentiation in acute leukaemia.
by: Catovsky, D.
Published: (1975)

Acidosis Sensing Receptor GPR65 Correlates with Anti-Apoptotic Bcl-2 Family Member Expression in CLL Cells: Potential Implications for the CLL Microenvironment
by: Rosko, Ashley E, et al.
Published: (2014)

Patients with chronic lymphocytic leukaemia (CLL) differ in the pattern of CTLA-4 expression on CLL cells: the possible implications for immunotherapy with CTLA-4 blocking antibody
by: Ciszak, Lidia, et al.
Published: (2015)

Role of stromal cell-mediated Notch signaling in CLL resistance to chemotherapy
by: Kamdje, A H Nwabo, et al.
Published: (2012)

Cannabinoid Receptors Are Overexpressed in CLL but of Limited Potential for Therapeutic Exploitation
by: Freund, Patricia, et al.
Published: (2016)

Análise Agregada dos Municípios Mineiros de Grande Porte Quanto à Adequação à Lei de Responsabilidade Fiscal (LRF)
by: Pablo Rogers, et al.
Published: (2007-01-01)

Deoxycoformycin in the treatment of mature B-cell malignancies.
by: Dearden, C., et al.
Published: (1990)

Alemtuzumab in the treatment of fludarabine refractory B-cell chronic lymphocytic leukemia (CLL)
by: Montillo, Marco, et al.
Published: (2008)