Role of stromal cell-mediated Notch signaling in CLL resistance to chemotherapy

Stromal cells are essential components of the bone marrow (BM) microenvironment that regulate and support the survival of different tumors, including chronic lymphocytic leukemia (CLL). In this study, we investigated the role of Notch signaling in the promotion of survival and chemoresistance of hum...

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Bibliographic Details
Main Authors: Kamdje, A H Nwabo, Bassi, G, Pacelli, L, Malpeli, G, Amati, E, Nichele, I, Pizzolo, G, Krampera, M
Format: Online
Language:English
Published: Nature Publishing Group 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3366070/