Role of stromal cell-mediated Notch signaling in CLL resistance to chemotherapy
Stromal cells are essential components of the bone marrow (BM) microenvironment that regulate and support the survival of different tumors, including chronic lymphocytic leukemia (CLL). In this study, we investigated the role of Notch signaling in the promotion of survival and chemoresistance of hum...
Main Authors: | , , , , , , , |
---|---|
Format: | Online |
Language: | English |
Published: |
Nature Publishing Group
2012
|
Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3366070/ |