Metabolic plasticity in CLL: adaptation to the hypoxic niche

Metabolic transformation in cancer is increasingly well understood. However, little is known about the metabolic responses of cancer cells that permit their survival in different microenvironments. We have used a nuclear magnetic resonance based approach to monitor metabolism in living primary chron...

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Bibliographic Details
Main Authors: Koczula, K M, Ludwig, C, Hayden, R, Cronin, L, Pratt, G, Parry, H, Tennant, D, Drayson, M, Bunce, C M, Khanim, F L, Günther, U L
Format: Online
Language:English
Published: Nature Publishing Group 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4705428/