Cross-talk between DNA methylation and active histone modifications regulates aberrant expression of ZAP70 in CLL

Cross-talk between DNA methylation and active histone modifications regulates aberrant expression of ZAP70 in CLL

Zeta-associated protein of 70 kD (ZAP70) is a recognized adverse prognostic marker in chronic lymphocytic leukaemia (CLL) associated with enhanced B-cell receptor signalling, significantly more aggressive disease course and poor overall survival. Zeta-associated protein of 70 kD is ordinarily expres...

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Bibliographic Details
Main Authors: Amin, Shilu, Walsh, Meagan, Wilson, Caroline, Parker, Anton E, Oscier, David, Willmore, Elaine, Mann, Derek, Mann, Jelena
Format: Online
Language:English
Published: Blackwell Publishing Ltd 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3822977/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3822977/

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