Polyethylene glycol binding alters human telomere G-quadruplex structure by conformational selection

Polyethylene glycol binding alters human telomere G-quadruplex structure by conformational selection

Polyethylene glycols (PEGs) are widely used to perturb the conformations of nucleic acids, including G-quadruplexes. The mechanism by which PEG alters G-quadruplex conformation is poorly understood. We describe here studies designed to determine how PEG and other co-solutes affect the conformation o...

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Bibliographic Details
Main Authors: Buscaglia, Robert, Miller, M. Clarke, Dean, William L., Gray, Robert D., Lane, Andrew N., Trent, John O., Chaires, Jonathan B.
Format: Online
Language:English
Published: Oxford University Press 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3763525/

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