Molecular dynamics and principal components of potassium binding with human telomeric intra-molecular G-quadruplex
Telomere assumes intra-molecular G-quadruplex that is a significant drug target for inhibiting telomerase maintenance of telomeres in cancer. Metal cations have been recognized as playing important roles in stabilizing G-quadruplex, but their binding processes to human telomeric G-quadruplex remain...
| Main Authors: | , , , , |
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| Format: | Online |
| Language: | English |
| Published: |
Higher Education Press
2015
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4444812/ |