Molecular engineering of G-quadruplex ligands based on solvent effect of polyethylene glycol

Because various non-parallel G-quadruplexes of human telomeric sequences in K+ solution can be converted to a parallel G-quadruplex by adding polyethylene glycol (PEG) as a co-solvent, we have taken advantage of this property of PEG to study the covalent attachment of a PEG unit to a G-quadruplex li...

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Bibliographic Details
Main Authors: Wang, Zi-Fu, Chang, Ta-Chau
Format: Online
Language:English
Published: Oxford University Press 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3458535/