Recognition of Chelerythrine to Human Telomeric DNA and RNA G-quadruplexes
A study on binding of antitumor chelerythrine to human telomeric DNA/RNA G-quadruplexes was performed by using DNA polymerase stop assay, UV-melting, ESI-TOF-MS, UV-Vis absorption spectrophotometry and fluorescent triazole orange displacement assay. Chelerythrine selectively binds to and stabilizes...
Main Authors: | , , , |
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Format: | Online |
Language: | English |
Published: |
Nature Publishing Group
2014
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4208030/ |