Thermodynamic fingerprints of ligand binding to human telomeric G-quadruplexes

Thermodynamic studies of ligand binding to human telomere (ht) DNA quadruplexes, as a rule, neglect the involvement of various ht-DNA conformations in the binding process. Therefore, the thermodynamic driving forces and the mechanisms of ht-DNA G-quadruplex-ligand recognition remain poorly understoo...

Full description

Bibliographic Details
Main Authors: Bončina, Matjaž, Podlipnik, Črtomir, Piantanida, Ivo, Eilmes, Julita, Teulade-Fichou, Marie-Paule, Vesnaver, Gorazd, Lah, Jurij
Format: Online
Language:English
Published: Oxford University Press 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4666371/