Compensatory dendritic cell development mediated by BATF-IRF interactions
The AP-1 transcription factor Batf3 is required for homeostatic development of CD8α+ classical dendritic cells that prime CD8 T-cell responses against intracellular pathogens. Here, we identify an alternative, Batf3-independent pathway for their development operating during infection with intracellu...
Main Authors: | Tussiwand, Roxane, Lee, Wan-Ling, Murphy, Theresa L., Mashayekhi, Mona, Wumesh, KC, Albring, Jörn C., Satpathy, Ansuman T., Rotondo, Jeffrey A., Edelson, Brian T., Kretzer, Nicole M., Wu, Xiaodi, Weiss, Leslie A., Glasmacher, Elke, Li, Peng, Liao, Wei, Behnke, Michael, Lam, Samuel S.K., Aurthur, Cora T., Leonard, Warren J., Singh, Harinder, Stallings, Christina L., Sibley, L. David, Schreiber, Robert D., Murphy, Kenneth M. |
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Format: | Online |
Language: | English |
Published: |
2012
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3482832/ |
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