RAB43 facilitates cross-presentation of cell-associated antigens by CD8α+ dendritic cells
RAB43 is a vesicular transport protein unique to CD8α+ DCs that is localized to the Golgi. Kretzer et al. show that RAB43 is necessary for optimal cross-presentation of cell-associated antigens by CD8α+ DCs in vitro and in vivo but that it is dispensable for cross-presentation by in vitro monocyte-d...
Main Authors: | , , , , , , , , , , |
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Format: | Online |
Language: | English |
Published: |
The Rockefeller University Press
2016
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5154939/ |