RAB43 facilitates cross-presentation of cell-associated antigens by CD8α+ dendritic cells

RAB43 is a vesicular transport protein unique to CD8α+ DCs that is localized to the Golgi. Kretzer et al. show that RAB43 is necessary for optimal cross-presentation of cell-associated antigens by CD8α+ DCs in vitro and in vivo but that it is dispensable for cross-presentation by in vitro monocyte-d...

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Bibliographic Details
Main Authors: Kretzer, Nicole M., Theisen, Derek J., Tussiwand, Roxane, Briseño, Carlos G., Grajales-Reyes, Gary E., Wu, Xiaodi, Durai, Vivek, Albring, Jörn, Bagadia, Prachi, Murphy, Theresa L., Murphy, Kenneth M.
Format: Online
Language:English
Published: The Rockefeller University Press 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5154939/