IRF4 and BATF are critical for CD8+ T-cell function following infection with LCMV

CD8+ T-cell functions are critical for preventing chronic viral infections by eliminating infected cells. For healthy immune responses, beneficial destruction of infected cells must be balanced against immunopathology resulting from collateral damage to tissues. These processes are regulated by fact...

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Bibliographic Details
Main Authors: Grusdat, M, McIlwain, D R, Xu, H C, Pozdeev, V I, Knievel, J, Crome, S Q, Robert-Tissot, C, Dress, R J, Pandyra, A A, Speiser, D E, Lang, E, Maney, S K, Elford, A R, Hamilton, S R, Scheu, S, Pfeffer, K, Bode, J, Mittrücker, H-W, Lohoff, M, Huber, M, Häussinger, D, Ohashi, P S, Mak, T W, Lang, K S, Lang, P A
Format: Online
Language:English
Published: Nature Publishing Group 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4207473/