L-Myc expression by dendritic cells is required for optimal T-cell priming

The transcription factors c-Myc and N-Myc encoded by Myc and Mycn, respectively, regulate cellular growth1 and are required for embryonic development2,3. A third paralog, Mycl1, is dispensable for normal embryonic development but its normal biologic function has remained unclear4. To examine the in...

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Bibliographic Details
Main Authors: Wumesh, KC, Satpathy, Ansuman T., Rapaport, Aaron S., Briseño, Carlos G., Wu, Xiaodi, Albring, Jörn C., Russler-Germain, Emilie V., Kretzer, Nicole M., Durai, Vivek, Persaud, Stephen P., Edelson, Brian T., Loschko, Jakob, Cella, Marina, Allen, Paul M., Nussenzweig, Michel C., Colonna, Marco, Sleckman, Barry P., Murphy, Theresa L., Murphy, Kenneth M.
Format: Online
Language:English
Published: 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3954917/