IL-6 activated integrated BATF/IRF4 functions in lymphocytes are T-bet-independent and reversed by subcutaneous immunotherapy

IL-6 activated integrated BATF/IRF4 functions in lymphocytes are T-bet-independent and reversed by subcutaneous immunotherapy

IL-6 plays a central role in supporting pathological TH2 and TH17 cell development and inhibiting the protective T regulatory cells in allergic asthma. TH17 cells have been demonstrated to regulate allergic asthma in general and T-bet-deficiency-induced asthma in particular. Here we found an inverse...

Full description

Bibliographic Details
Main Authors: Koch, Sonja, Mousset, Stephanie, Graser, Anna, Reppert, Sarah, Übel, Caroline, Reinhardt, Cornelia, Zimmermann, Theodor, Rieker, Ralf, Lehr, Hans A., Finotto, Susetta
Format: Online
Language:English
Published: Nature Publishing Group 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3639449/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3639449/

Similar Items