Quantitative profiling of BATF family proteins/JUNB/IRF hetero-trimers using Spec-seq

Abstract Background BATF family transcription factors (BATF, BATF2 and BATF3) form hetero-trimers with JUNB and either IRF4 or IRF8 to regulate cell fate in T cells and dendritic cells in vivo. While each combination of the hetero-trimer has a distinct role, some degree of cross-compensation was obs...

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Bibliographic Details
Main Authors: Yiming K. Chang, Zheng Zuo, Gary D. Stormo
Format: Article
Language:English
Published: BioMed Central 2018-03-01
Series:BMC Molecular Biology
Subjects:
IRF
Online Access:http://link.springer.com/article/10.1186/s12867-018-0106-7