Myo1c binding to submembrane actin mediates insulin-induced tethering of GLUT4 vesicles
Insulin reduces the velocity of mobile Myo1c-positive GLUT4 vesicles beneath the muscle cell plasma membrane as visualized by total internal reflection fluorescence microscopy. Binding of vesicle-bound Myo1c to actin filaments underlies Myo1c's participation in GLUT4 vesicle tethering for subse...
Main Authors: | Boguslavsky, Shlomit, Chiu, Tim, Foley, Kevin P., Osorio-Fuentealba, Cesar, Antonescu, Costin N., Bayer, K. Ulrich, Bilan, Philip J., Klip, Amira |
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Format: | Online |
Language: | English |
Published: |
The American Society for Cell Biology
2012
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3469521/ |
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