Myo1c binding to submembrane actin mediates insulin-induced tethering of GLUT4 vesicles

Myo1c binding to submembrane actin mediates insulin-induced tethering of GLUT4 vesicles

Insulin reduces the velocity of mobile Myo1c-positive GLUT4 vesicles beneath the muscle cell plasma membrane as visualized by total internal reflection fluorescence microscopy. Binding of vesicle-bound Myo1c to actin filaments underlies Myo1c's participation in GLUT4 vesicle tethering for subse...

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Bibliographic Details
Main Authors: Boguslavsky, Shlomit, Chiu, Tim, Foley, Kevin P., Osorio-Fuentealba, Cesar, Antonescu, Costin N., Bayer, K. Ulrich, Bilan, Philip J., Klip, Amira
Format: Online
Language:English
Published: The American Society for Cell Biology 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3469521/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3469521/

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