Muscle cells challenged with saturated fatty acids mount an autonomous inflammatory response that activates macrophages

Obesity is associated with chronic low-grade inflammation. Within adipose tissue of mice fed a high fat diet, resident and infiltrating macrophages assume a pro-inflammatory phenotype characterized by the production of cytokines which in turn impact on the surrounding tissue. However, inflammation i...

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Bibliographic Details
Main Authors: Pillon, Nicolas J, Arane, Karen, Bilan, Philip J, Chiu, Tim T, Klip, Amira
Format: Online
Language:English
Published: BioMed Central 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3507850/