Electrical Stimuli Release ATP to Increase GLUT4 Translocation and Glucose Uptake via PI3Kγ-Akt-AS160 in Skeletal Muscle Cells

Electrical Stimuli Release ATP to Increase GLUT4 Translocation and Glucose Uptake via PI3Kγ-Akt-AS160 in Skeletal Muscle Cells

Skeletal muscle glucose uptake in response to exercise is preserved in insulin-resistant conditions, but the signals involved are debated. ATP is released from skeletal muscle by contractile activity and can autocrinely signal through purinergic receptors, and we hypothesized it may influence glucos...

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Bibliographic Details
Main Authors: Osorio-Fuentealba, Cesar, Contreras-Ferrat, Ariel E., Altamirano, Francisco, Espinosa, Alejandra, Li, Qing, Niu, Wenyan, Lavandero, Sergio, Klip, Amira, Jaimovich, Enrique
Format: Online
Language:English
Published: American Diabetes Association 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3636621/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3636621/

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